Category Archives: Skin cancer

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Berlin Die Zahl der diagnostizierten Hautkrebsfälle in Deutschland steigt rasant an. Im Jahr 2012 waren rund 1,56 Millionen Menschen von bösartigen Neubildungen der Haut betroffen, wie aus dem am Dienstag in Berlin veröffentlichten Arztreport der Barmer GEK hervorgeht. An der … Continue reading

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  SKCIN Guide to Safer Tanning On Holiday – Virgin Holidays. Virgin Holidays to promote sensible tanning Max Your Holiday Mojo and Feel Bronzed and Beautiful Just make sure you’re sun savvy So you’ve booked your holiday – now what … Continue reading

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http://well.blogs.nytimes.com/2013/05/27/the-new-rules-for-sunscreen/ There is no question most skin cancers are related to sun exposure, yet even with sunscreen sales approaching $1 billion a year, skin cancer rates continue to climb. Melanoma diagnoses have risen nearly 2 percent a year since 2000 … Continue reading

The Skin Cancer Foundation – Breakthrough Melanoma Drug Approved— First in a New Class of “Targeted” Treatments | melanoma

 The US Food and Drug Administration (FDA) has approved a new drug — the first of its kind — for the treatment of inoperable or advanced metastatic (spreading) melanoma. Melanoma is the deadliest form of skin cancer. The drug, called Zelboraf, was found to delay disease progression and extend life significantly.

“For patients with advanced melanoma, Zelboraf means hope — extending life for months, and in some cases, years,” said Rex Amonette, MD, Senior Vice President of The Skin Cancer Foundation. “Zelboraf represents yet another significant recent medical advancement in the fight against this disease, which claims 8,700 American lives each year.”

Zelboraf (a.k.a. vemurafenib, or PLX 4032) is the first targeted genetic therapy for melanoma approved to date. It is approved for patients whose tumors harbor a mutation (defect) in the BRAF V600E gene, which is present in about 40-60 percent of melanomas. By inhibiting the defective BRAF gene, Zelboraf slows or halts the uncontrolled (cancerous) cell growth associated with the gene mutation.

In an early clinical trial, Zelboraf was successful in shrinking the tumors of 81 percent of patients who had the mutation, the greatest response rate a melanoma drug has ever had. In more recent trials of melanoma patients, all of whom had the mutated gene, those who received Zelboraf were 56 percent less likely to die in the study period than those who received standard chemotherapy. Average overall survival for patients receiving Zelboraf could not be determined because so many patients remained alive; in contrast, average survival for patients on chemotherapy was only 7.9 months. Patients on Zelboraf were also 74 percent less likely to see their disease advance compared with patients on chemotherapy.

Along with Zelboraf, the FDA approved the cobas 4800 BRAF V600 Mutation Test, which determines if a patient has the BRAF mutation and is eligible for the treatment. Zelboraf is taken orally, and the prescribed dose is 960 mg twice a day. The drug is marketed by Roche’s Genentech, and will be available within two weeks.

via The Skin Cancer Foundation – Breakthrough Melanoma Drug Approved— First in a New Class of “Targeted” Treatments | melanoma.

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How to Watch for Signs of Skin Cancer – WSJ.com. From the Wall Street Journal. October 31 2011.  Patricia Landsberg, always a sun worshipper, embraced outdoor living when she moved to Bradenton, Fla., 22 years ago: a waterfront home, boating, … Continue reading

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The Press Association: Skin cancer study in gene discovery.

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 Understanding the genetic basis of melanoma. An international study published today in Nature Genetics, has discovered two genetic variants that increase the risk of melanoma. Melanoma is not the most common type of skin cancer but it is one of … Continue reading

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 The Skin Cancer Foundation – California Enacts Nation’s Strictest Teen Tanning Law | Tanning. Children under the age of 18 have been banned from indoor ultraviolet (UV) tanning in California. On October 9, 2011, Governor Jerry Brown signed the bill … Continue reading

The Skin Cancer Foundation – Guidelines

Understanding Sunburn

Sunburn
Unlike instantaneous burns from touching a heat source, sunburn inflammation and redness usually start about four hours after exposure. Maximum redness generally occurs within 12 to 24 hours, and the painful, burning sensation occurs from 6 to 48 hours after exposure. After a couple days, the outer layers of skin may peel away. Peeling is actually the body’s way of healing itself by shedding the top layer of damaged epidermis.

Severe sunburns can cause chills, fever, nausea, and blistering in various degrees. In cases in which people are stranded without shelter, extremely severe sunburns can cause what is known as sun poisoning. Sun poisoning may be life threatening. It results in severe blistering, a lack of fluids, an imbalance in important chemicals, and it may even lead to deadly infections.

Follow this link to watch a really good animation video explaining sunburn, from Skincancer.org
The Skin Cancer Foundation – Sunburn.

What is Melanotan and how does it work? : Cancer Research UK

What is Melanotan and how does it work? 

As published by Cancer Research UK

Melanotan is a synthetic hormone that works by increasing the levels of melanin, a natural dark pigment in the skin. Melanin causes the skin to darken or tan. It provides a small amount of protection against sun exposure. There are two types of Melanotan – Melanotan I and Melanotan II.

It is currently illegal to sell tan injections such as Melanotan. This is because this product is unlicensed as it has not been safety tested so we do not know if this drug has any side effects or how serious they could be.

Why is it illegal?

Melanotan is illegal in the UK because:

  • It has not been tested for safety, quality or effectiveness.
  • No one knows what the possible side effects are or how serious they could be.

The MHRA (Medicines and Healthcare products Regulatory Agency) tests medical products in the UK. They are warning people not to use Melanotan and they say that the product is being “advertised and sold illegally”.

David Carter, from the MHRA said:

“We are warning people not to use this product. Don’t be fooled into thinking that Melanotan offers a shortcut to a safer and more even tan. The safety of these products is unknown and they are unlicensed in the UK. The side effects could be extremely serious. If you have used either of these products do not use them again and if you have any concerns you should seek advice from your doctor.”

For more information on this post please follow this link:
What is Melanotan and how does it work? : Cancer Research UK.